METHOD OF PRODUCING COLLAGEN PARTICLES, AND THE USE OF SUCH PARTICLES AS SUBSTRATES FOR ACTIVE SUBSTANCES

摘要

The invention concerns a process for the production of cross-linked collagen particles whose size lies in the micro and nanometer range, in which a solution or disper- sion of collagen in water is distributed finely in discrete droplets in a waterimmiscible organic phase, whereby emul- sifying agents are added, a water-in-oil emulsion thereby being formed, the collagen being subsequently cross-linked in the interface of the droplets, using a cross-linking agent, and the collagen particles produced in this manner being purified and isolated by separating the organic phase and washing.