发明名称 METHOD FOR PREPARING MICROPARTICLES HAVING A SELECTED POLYMER MOLECULAR WEIGHT
摘要 A method for preparing microparticles having a selected polymer molecular weight. The hold time and temperature of a solution containing a nucleophilic compound and a polymer having a starting molecular weight are controlled in order to control the molecular weight of the polymer in the finished microparticle product. In this manner, a selected polymer molecular weight in the finished microparticle product can be achieved from a variety of starting material molecular weights.
申请公布号 WO0189482(A2) 申请公布日期 2001.11.29
申请号 WO2001US12654 申请日期 2001.04.19
申请人 ALKERMES CONTROLLED THERAPEUTICS INC. II 发明人 WRIGHT, STEVEN, G.;RICKEY, MICHAEL, E.;RAMSTACK, J., MICHAEL;LYONS, SHAWN, L.;HOTZ, JOYCE, M.
分类号 C07D489/08;A61K9/16;A61K9/50;A61K31/216;A61K31/485;A61K31/519;A61K47/34;B01J13/02;C07D471/04;C08G63/06 主分类号 C07D489/08
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