发明名称 |
Complexes and combinations of fetuin with therapeutic agents |
摘要 |
There is disclosed a complex and a combination of the glycosylated polypeptide fetuin and a therapeutically active small molecule compound having a net positive charge at physiological pH. The presence of fetuin as a drug complex or in combination with the therapeutically active small molecule compound enhances therapeutic activity of the small molecule compound. The present invention further provides a means for screening for therapeutically active small molecule compounds by means of binding to fetuin.
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申请公布号 |
US6319894(B1) |
申请公布日期 |
2001.11.20 |
申请号 |
US19970780311 |
申请日期 |
1997.01.08 |
申请人 |
THE PICOWER INSTITUTE FOR MEDICAL RESEARCH |
发明人 |
TRACEY KEVIN;WANG HAICHAO |
分类号 |
A61K45/08;A61K38/00;C07K14/47;C07K14/71;(IPC1-7):A61K31/167;A61K38/17;C07K251/74;C07K251/86 |
主分类号 |
A61K45/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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