发明名称 CYCLIC AMINE, METHOD OF PRODUCING THE SAME AND USE THEREOF
摘要 PROBLEM TO BE SOLVED: To provide a compound that shows excellent CCR5 antagonistic action and is useful as a prophylactic and therapeutic agent for the HIV infection to human peripheral blood mononuclear cells, particularly for AID. SOLUTION: This invention is the compound represented by formula 1 or salts thereof. As a compound of this invention, are cited N-(3- chlorophenyl)-1-(methyl-sulfonyl)-N- 3-[4-( 4-[(methylsulfonyl)amino]phenyl}- sulfonyl)-1-piperidinyl]propyl)-4-piperidinecarbo-xamide, N-(3,4- dichlorophenyl)-1-(methylsulfonyl)-N- 3-[4-( 4-[(methylsulfonyl)amino]phenyl) sulfonyl)-1-piperidinyl]propyl)-4-piperidinecarboxamide.
申请公布号 JP2001302633(A) 申请公布日期 2001.10.31
申请号 JP20000302841 申请日期 2000.09.29
申请人 TAKEDA CHEM IND LTD 发明人 IMAMURA SHINICHI;HASHIGUCHI SHOHEI;HATTORI TAEKO;NISHIMURA TADASHI;KANZAKI NAOYUKI;BABA MASANORI;SUGIHARA YOSHIHIRO
分类号 C07D211/62;A61K;A61K31/427;A61K31/4355;A61K31/437;A61K31/4427;A61K31/443;A61K31/4433;A61K31/445;A61K31/454;A61K31/4545;A61K31/4709;A61K31/472;A61K31/4725;A61K31/496;A61K31/497;A61K31/498;A61K31/5025;A61K31/506;A61K31/513;A61K31/5377;A61K31/5513;A61K31/7072;A61K31/708;A61K45/00;A61P;A61P31/18;A61P43/00;C07D;C07D211/58;C07D211/70;C07D211/74;C07D211/96;C07D401/12;C07D401/14;C07D405/12;C07D405/14;C07D409/14;C07D413/12;C07D413/14;C07D417/04;C07D417/14;C07D471/04;C07D471/14;C07D471/16;C07D487/04;C07D487/14;(IPC1-7):C07D211/62;A61K31/502;A61K31/537;A61K31/551;A61K31/707 主分类号 C07D211/62
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