ANTIBIOTICS TRIPROPEPTINS AND PROCESS FOR PRODUCING THE SAME

摘要

By culturing Lysobacter sp. BMK333-48F3 (Accession No. FERM BP-7477), antibiotics tripropeptin Z, tripropeptin A, tripropeptin B, tripropeptin C and tripropeptin D represented by general formula (I) are obtained as antibiotics showing an excellent antibacterial effect on bacteria and having a novel molecular skeleton, wherein R represents 7-methyl-octyl, 8-methyl-nonyl, 9-methyl-decyl, 10-methyl-undecyl or 11-methyl-dodecyl. These tripropeptins have an excellent antibacterial activity on various bacteria and drug-tolerant strains thereof such as methicillin-tolerant strains and vancomycin-tolerant strains.