发明名称 |
MANGANESE SUPEROXIDE DISMUTASE GENE POLYMORPHISM FOR PREDICTING CANCER SUSCEPTIBILITY |
摘要 |
The invention provides a method for determining the colorectal cancer susceptibility of a patient comprising determining a patient's genotype at the manganese superoxide dismutase (MnSOD) gene locus, wherein a patient with one or two alleles encoding alanine at position -9 of the signal peptide has an increased risk of developing colorectal cancer. Also provided are nucleic acid probes and kits for determining a patient's colorectal cancer risk.
|
申请公布号 |
WO0175175(A2) |
申请公布日期 |
2001.10.11 |
申请号 |
WO2001US10873 |
申请日期 |
2001.04.02 |
申请人 |
UNIVERSITY OF SOUTHERN CALIFORNIA;LENZ, HEINZ-JOSEF;STOEHLMACHER, JAN |
发明人 |
LENZ, HEINZ-JOSEF;STOEHLMACHER, JAN |
分类号 |
C07H21/02;C07H21/04;C12P19/34;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
C07H21/02 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|