16835, A NOVEL HUMAN PHOSPHOLIPASE C FAMILY MEMBER AND USES THEREOF

摘要

The invention provides isolated nucleic acids molecules, designated 16835 nucleic acid molecules, which encode novel phospholipase C members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 16835 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 16835 gene has been introduced or disrupted. The invention still further provides isolated 16835 proteins, fusion proteins, antigenic peptides and anti-16835 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.