发明名称 Verfahren zur Herstellung von Nanosuspensionen
摘要 The invention relates to a method for producing nanosuspensions. According to said method, at least two dosed partial streams (25, 26) are brought into contact in such a way that they are subjected to a thorough mixing induced by turbulence. In said process, the partial streams have a flow rate ranging between 0.1 and 500 ml/h and the mixed stream has a combined flow rate ranging between 1 ml/h and 500 ml/h. During the turbulent mixing process particles are created with a size of between 0.1 and 5000 nm. The invention also relates to a method for the in-situ formulation of a medicament suspension, whereby the medicament suspension is administered continuously by means of a line.
申请公布号 DE10007816(A1) 申请公布日期 2001.09.06
申请号 DE20001007816 申请日期 2000.02.21
申请人 BAYER AG 发明人 KUEHN, BERND;JUERGENS, KAI CHRISTIAN;WIESMEIER, GEORG
分类号 A61K9/10;A61K9/14;B01F3/12;B01F5/00;B01F5/02;B01F5/06;B01F13/00;(IPC1-7):B01F3/12;B01J13/00;B01J19/26 主分类号 A61K9/10
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