发明名称 Production of new polymer liquid crystals capable of having an interaction with liposomes
摘要 Process comprising the following steps: (a) preparation of liposomes (bilayers) by extrusion from lipids, such as dimiristoylphosphatidylcholine; (b) preparation of polymers (-) PTOBEE (C26H20O8)n, both being liquid crystals of the cholesteric type; ( ) addition of the polymers to the suspension of liposomes. These systems have biomedical and pharmacologic applications such as "stealth liposomes', or "ghost liposomes', for the encapsulation of drugs with, as a result, an extension of their average life in the blood flow."
申请公布号 US6277403(B1) 申请公布日期 2001.08.21
申请号 US19990355090 申请日期 1999.09.22
申请人 CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS 发明人 PéREZ MéNDEZ MARíA MERCEDES;MATEO MARTíNEZ CARMEN REYES
分类号 A61K9/127;A61K9/48;A61K47/24;A61K47/34;C08G63/185;C09K19/38;(IPC1-7):A61K1/127 主分类号 A61K9/127
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