发明名称 |
IDENTIFICATION OF PERIPHERAL BENZODIAZEPINE RECEPTOR BINDINGAGENTS |
摘要 |
The invention provides methods for screening for agents that modulate mitochondrial membrane potential. Such agents generally bind to a peripheral benzodiazepine receptor and may be detected by direct binding assays or by indirect or functional assays. Agents identified using the screens provided herein have application in the prevention and treatment of a variety of diseases associated with abnormal mitochondrial function.
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申请公布号 |
CA2406901(A1) |
申请公布日期 |
2001.07.19 |
申请号 |
CA20012406901 |
申请日期 |
2001.01.16 |
申请人 |
MITOKOR |
发明人 |
VELICELEBI, GONUL;SJOBERG, ERIC R. |
分类号 |
C12N5/10;C12N15/09;C12Q1/02;G01N33/15;G01N33/50;G01N33/566;G01N33/94;(IPC1-7):C12N5/10 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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