摘要 |
<p>The invention provides a method for reducing the level of active pathogenic contaminants, such as viruses, bacteria and parasites, found in whole blood and blood components. The method comprising adding to whole blood or blood components at least one phenothiazin-5-ium dye in an amount effective to reduce the level of active pathogenic contaminants and irradiating the whole blood or blood components with light of an appropriate intensity and wavelength for a time sufficient to reduce the level of the active pathogenic contaminants in the whole blood or blood components, wherein the partial pressure of oxygen in the whole blood or blood components is maintained at a level during the irradiation such that the amount of active pathogenic contaminants in the whole blood or blood components is reduced.</p> |