发明名称 |
Verfahren zur Herstellung von Aspartase und L-Asparginsäure |
摘要 |
Disclosed are a process for producing aspartase which comprises culturing a microorganism belonging to the genus Escherichia being capable of producing aspartase in a medium until aspartase is produced and accumulated in the culture, and recovering aspartase therefrom, wherein dissolved oxygen concentration of the medium is in the range of 0 to 1 ppm on the stage that microbial growth is middle and/or late logarithmic growth phase; and a process for producing L-aspartic acid which comprises converting fumaric acid and ammonia into L-aspartic acid in an aqueous medium in the presence of an enzyme source, wherein said enzyme source is a culture produced in accordance with said aspartase-producing process, cells isolated from the culture, or processed cells thereof. |
申请公布号 |
DE69704900(D1) |
申请公布日期 |
2001.06.28 |
申请号 |
DE1997604900 |
申请日期 |
1997.03.18 |
申请人 |
KYOWA HAKKO KOGYO CO., LTD. |
发明人 |
TAKANO, JUNICHI;KINO, KUNIKI |
分类号 |
C12N9/88;C12P13/20 |
主分类号 |
C12N9/88 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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