发明名称 |
Controlled release composition comprising a sustained release layer and a fast release layer |
摘要 |
The present invention provides a composition comprising a sustained release layer and a fast release layer. The sustained release layer comprises a water-soluble polymer and a first pharmaceutically active agent. The fast release layer comprises a matrix forming agent and a second pharmaceutically active agent. Generally, the composition provides fast and sustained (or controlled) release of a pharmaceutically active agent for at least 6 hours and preferably for at least 1 to 3 days. The composition may be incorporated into a dosage unit form, such as a vaginal insert. The compositions are prepared by freeze-drying. |
申请公布号 |
EP1110541(A1) |
申请公布日期 |
2001.06.27 |
申请号 |
EP20000311631 |
申请日期 |
2000.12.22 |
申请人 |
JOHNSON & JOHNSON CONSUMER COMPANIES, INC. |
发明人 |
LIN, SHUN Y;WEARLEY, LORRAINE L.;GOLE, DILIP J.;POSAGE, GARY W.;WILKINSON, PAUL K. |
分类号 |
A61K9/02;A61K9/00;A61K9/08;A61K9/19;A61K9/20;A61K9/22;A61K9/24;A61K47/26;A61K47/34;A61K47/36;A61K47/42;C08J3/00;C08J3/21;C08K5/00;C08L101/00;C08L101/14 |
主分类号 |
A61K9/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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