发明名称 7-[(4-TRIFLUOROMETHYL-BIPHENYL-2-CARBONYL)AMINO]- QUINOLINE-3-CARBOXAMIDE AND METHOD FOR INHIBITING SECRETION OF APOLIPOPROTEIN B
摘要 PROBLEM TO BE SOLVED: To obtain a compound and a pharmaceutical composition for the treatment and/or prophylaxis of atherosclerosis, obesity, diabetes, hyperlipemia, hyperlipoproteinemia, hypercholesterolemia, hypertriglyceridemia, hypoalphalipoproteinemia, pancreatitis, cardiac infarction, fit, restenosis or X-ray syndrome and to provide a method therefor. SOLUTION: This compound is represented by the formula I and capable of inhibiting the secretion of apolipoprotein B. The pharmaceutical composition comprises the compound. The method comprises a step of administering an effective amount of the compound or composition to patients.
申请公布号 JP2001139555(A) 申请公布日期 2001.05.22
申请号 JP20000344267 申请日期 2000.11.10
申请人 PFIZER PROD INC 发明人 PETER BAATINAT;HAMANAKA ERNEST SEIICHI;RUGGERI ROGER BENJAMIN;WILSON DOUGLAS PAUL
分类号 A61K31/47;A61K31/4709;A61K45/00;A61P1/18;A61P3/04;A61P3/06;A61P3/10;A61P9/00;A61P9/10;A61P43/00;C07D215/54;C07D401/12;C07D401/14;C07D405/12;C07D405/14;C07D409/12;(IPC1-7):C07D215/54 主分类号 A61K31/47
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