METHOD FOR PURIFYING FUSED PROTEIN OF IL-6R AND IL-6

摘要

PROBLEM TO BE SOLVED: To provide a method for purifying a fused protein of IL-6R and IL-6 in industrial scale and high purity without causing denaturation and deactivation. SOLUTION: This method for purifying a fused protein of IL-6R with IL-6 comprises bringing a solution containing the fused protein of IL-6R with IL-6 into contact with absorbent particles floating in a fluid bed, feeding the eluent and eluting and recovering absorbed fraction to the adsorbent particles.