发明名称 |
HETEROCYCLIC COMPOUNDS USEFUL AS INHIBITORS OF TYROSINE KINASES |
摘要 |
Disclosed are novel compounds of formula (I) wherein Ar1, Ra, R4, R5, X and Y are defined below, which are useful as inhibitors of certain protein tyrosin a kinases and are thus useful for treating diseases associated with such kinases, for example, diseases resulting from inappropriate cell proliferation, which include autoimmune diseases, chronic inflammatory diseases, allergic diseases, transplant rejection and cancer. Also disclosed are processes for preparing these compounds, novel intermediates useful in these processes and compositions comprising compounds of formula (I).</SDOAB >
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申请公布号 |
CA2384378(A1) |
申请公布日期 |
2001.04.12 |
申请号 |
CA20002384378 |
申请日期 |
2000.10.05 |
申请人 |
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. |
发明人 |
MOSS, NEIL;HAMMACH, ABDELHAKIM;PROKOPOWICZ, ANTHONY, S., III;SNOW, ROGER, JOHN;CARDOZO, MARIO, GUSTAVO;GOLDBERG, DANIEL;TAKAHASHI, HIDENORI;TSCHANTZ, MATT, AARON;WANG, XIAO-JUN;MORWICK, TINA;PATEL, USHA, R. |
分类号 |
A61K31/444;A61K31/4545;A61K31/4745;A61K31/496;A61K31/5377;A61P1/04;A61P3/10;A61P9/10;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P19/08;A61P19/10;A61P25/28;A61P29/00;A61P35/00;A61P37/02;A61P37/06;A61P41/00;A61P43/00;C07D217/24;C07D235/30;C07D471/04;C07D491/20;C07D513/04;C07D519/00;(IPC1-7):C07D471/04;C07D221/00;C07D235/00;C07D277/00;C07D513/00;C07D498/04;A61K31/435;A61K31/437 |
主分类号 |
A61K31/444 |
代理机构 |
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代理人 |
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地址 |
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