摘要 |
PROBLEM TO BE SOLVED: To provide anα-substituted carboxylic acid derivative, its pharmacologically acceptable ester or its pharmacologically acceptable amide compound or its pharmacologically acceptable salt which is useful as a medicine for treating and/or preventing diabetes, impaired glucose tolerance, gestational diabetes and so on. SOLUTION: Anα-substituted carboxylic acid derivative of general formula (I) (R1 is an alkyl or the like; R2 is H or the like; R3 is H or the like; A is CH or the like; B is oxygen atom or the like; W1 is a 1 to 8C alkylene; W2 is a single bond or a 1 to 8C alkylene; X is H or the like; Y is oxygen atom or the like; Z1 is an alkoxy or the like), its pharmacologically acceptable salt, its pharmacologically acceptable ester or its pharmacologically acceptable amide compound.
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