BENZOPYRAN DERIVATIVE

摘要

This invention relates a benzopyran derivative of formula (I) wherein, R<1> and R<2> represent each independently a hydrogen atom, a (substituted)C1-6 alkyl group or a (substituted)phenyl group,R<3> represents a hydroxyl group or C1-6 alkylcarbonyloxy group, R<4> represents a hydrogen atom, or R<3> and R<4> together form a bond, m represents an integer of 0-4, n represents an integer of 0-4, Y is absent, or represents CR<11>R<12> in which R<11> and R<12> represent each independently a hydrogen atom or a C1-6 alkyl group, R<5> represents an aryl group or a (substituted)heteroaryl group,R<6> represents a hydrogen atom or a C1-6 alkyl group,R<7> represents a hydrogen atom or a C1-6 alkyl group,X is absent, or represents C=O or SO2, R<8> represents a hydrogen atom, a (substituted)C1-6 alkyl group or C<3-6> cycloalkyl group, and R<9> represents a nitro group, etc., or a pharmaceutically acceptable salt thereof. And this invention also relates an antiarrhythmic agent having the prolongation effect on the functional refractory period comprising said compound or a pharmaceutically acceptable salt thereof as an active ingredient.