Process for producing substituted alkylamines or salts thereof

摘要

The present invention provides a process for producing a substituted alkylamine represented by formula (3):or a salt thereof, which process comprises reacting a 2-aminothiophenol derivative metal salt represented by formula (1):with an amino acid-N-carboxy anhydride represented by formula (2):and then subjecting the reaction product to cyclization under an acidic condition. A substituted alkylamine typified by 1-(2-benzothioazolyl)akylamine, or a salt thereof can be produced from a 2-aminothiophenol derivative industrially at a high handleability and a high yield, and even when the intended substituted alkylamine is an optically active compound, the intended product can be produced without reducing the optical purity of the optically active raw material.