POLYMORPHISM IN A NITRIC OXIDE SYNTHASE GENE

摘要

A method of diagnosis of disease or predisposition to disease, in particular Syndrome X or a component thereof such as hypertension, comprising genotyping an inducible nitric oxide synthase gene. The presence of a four base insertion polymorphism in the promoter region of said gene denotes an individual with increased risk of disease, in particular hypertension and/or the group of conditions known as Syndrome X.