| 摘要 |
PROBLEM TO BE SOLVED: To provide an intermediate capable of giving a (+)-estrone derivative from a dicyclopentadiene derivative with small number of steps in high total yield. SOLUTION: The objective compound of formula (R is a 1-20C alkyl) can be produced by using (-)-tricyclo[5.2.1.02.6]deca-4,8-dien-3-one as a starting substance and carrying out asymmetric Diels-Alder reacting with a 4-vinyl-7- alkoxy-1,2-dihydronaphthalene. The derivative of the compound can be produced by subjecting the product to successive reaction steps. |
