发明名称 |
Peptido-mimetic compounds containing RGD sequence useful as integrin inhibitors |
摘要 |
<p>The present invention discloses compounds of formula (I) <CHEM> wherein n is the number 0, 1 or 2. There are also disclosed processes for the preparation of said compounds, together with methods for treating pathologies related to an altered alpha v beta 3 integrin-mediated cell attachment, in particular wherein the inhibition of angiogenesis is desired, for example in tumors, also associated with metastasis.</p> |
申请公布号 |
EP1077218(A2) |
申请公布日期 |
2001.02.21 |
申请号 |
EP20000830535 |
申请日期 |
2000.07.27 |
申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. |
发明人 |
SCOLASTICO, CARLO;GIANNINI, GIUSEPPE |
分类号 |
A61K38/00;A61P13/12;A61P19/10;A61P27/02;A61P35/00;A61P35/04;A61P43/00;C07B53/00;C07B61/00;C07K5/00;C07K5/078;C07K5/093;C07K7/64;(IPC1-7):C07K7/56 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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