| 摘要 |
A pharmaceutical composition comprising a compound of the general formula (I): (see formula I) wherein R1 and R2 are, independently, a hydrogen atom, a saturated or unsaturated aliphatic acyl having 2 to 25 carbon atoms or benzoyl group and R3 is a hydrogen atom or alkyl group, and a pharmaceutically acceptable carrier is disclosed. Further, a novel compound of the general formula (I) wherein R1 and R2 are, independently, a hydrogen atom, pivaloyl, capryloyl, lauroyl, palmitoyl, stearoyl, linoleoyl, docosahexaenoyl, or benzoyl group, and R3 is a hydrogen atom or methyl group, is also disclosed. The pharmaceutical composition is useful as a chondroprotective agent for prohibiting the destruction of,articular cartilage.
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