发明名称 |
ANTIPSYCHOTIC CYCLIC N-ARALKYL AMINES |
摘要 |
The invention concerns antipsychotic compounds of formula (I) wherein: A represents a group selected among the following: -C.ident.C-; -CH=CH-; -CH2- CH2-; n is equal to 1 or 2; X represents a hydrogen, chlorine or fluorine atom, a methyl or methoxy group; Y represents a hydrogen atom or a chlorine or a fluorine atom; R1 represents a cyclohexyl, phenyl, cycloheptyl, tertiary butyl, dicyclopropylmethyl, bicyclo[3.2.1]octanyl, 4-tetrahydropyranyl, 4- tetrahydrothiopyranyl or adamantyle group; R2 and R3 form together with the nitrogen atom whereto they re bound a cyclic amine; and the additive salts o f said compounds with pharmaceutically acceptable acids, as well as their solvates and hydrates.
|
申请公布号 |
CA2376691(A1) |
申请公布日期 |
2001.01.11 |
申请号 |
CA20002376691 |
申请日期 |
2000.06.27 |
申请人 |
SANOFI-SYNTHELABO |
发明人 |
PONCELET, MARTINE;VERNIERES, JEAN-CLAUDE;BOIGEGRAIN, ROBERT;PAUL, RAYMOND;BOURRIE, MARTINE;LAIR, PIERRE |
分类号 |
C07D295/02;A61K31/395;A61K31/4453;A61K31/55;A61P25/00;A61P25/18;A61P43/00;C07B61/00;C07D295/03;C07D295/06;C07D295/073;C07D295/08;C07D295/096;(IPC1-7):C07D295/06 |
主分类号 |
C07D295/02 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|