| 摘要 |
<p>The invention relates to derivatives of 4'-demycarosyl-8a-aza-8a-homotylosin of formula (I) wherein R represents CHO, CH(OCH3)2) or CH2N[CH2(C6H5)]2, R1 represents H or C¿1?-C3 acyl, R?2¿ represents OR?6 and R6¿ represents H or C¿1?-C3 acyl, R?3¿ represents H or R?2 and R3¿ together represent =O, R4 represents OH, R5 represents H or R?4 and R5¿ together represent =O, and to a process for the preparation thereof. Novel derivatives show antibacterial action and may also be used as intermediates for preparing novel 17-membered azalide antibiotics.</p> |
