摘要 |
A compound represented by general formula (I), a pharmaceutically acceptable acid addition salt thereof or a pharmaceutically acceptable C1-C6 alkyl addition salt thereof, and their medical applications. Since these compounds inhibit the action of chemokines such as MIP-1 alpha and/or MCP-1 on target cells, they may be useful as a therapeutic drug and/or preventative drug in diseases, such as atherosclerosis, rheumatoid arthritis, and the like where blood monocytes and lymphocytes infiltrate into tissues. |
申请人 |
TEIJIN LIMITED;DUPONT PHARMACEUTICALS RESEARCH LABORATORIES;SHIOTA, TATSUKI;FURUYA, MINORU;IMAI, MINORU;SAKAI, MITSURU;MUROGA, YUMIKO;SUDOH, MASAKI;TARBY, CHRISTINE, M.;SAIAH, EDDINE |
发明人 |
SHIOTA, TATSUKI;FURUYA, MINORU;IMAI, MINORU;SAKAI, MITSURU;MUROGA, YUMIKO;SUDOH, MASAKI;TARBY, CHRISTINE, M.;SAIAH, EDDINE |