发明名称 |
Primary phosphoramidate internucleoside linkages and oligonucleotides containing the same |
摘要 |
The invention provides new primary phosphoramidate internucleoside linkages that are less sterically constrained than existing phosphoramidate linkages, as well as oligonucleotides containing such linkages and processes for making and methods for using such oligonucleotides.
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申请公布号 |
US6140482(A) |
申请公布日期 |
2000.10.31 |
申请号 |
US19950519318 |
申请日期 |
1995.08.25 |
申请人 |
HYBRIDON, INC. |
发明人 |
IYER, RADHAKRISHNAN P.;DEVLIN, THERESA;HABUS, IVAN;YU, DONG;AGRAWAL, SUDHIR |
分类号 |
C07H19/10;C07H19/16;C07H19/20;C07H21/00;(IPC1-7):C07H21/00 |
主分类号 |
C07H19/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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