| 发明名称 |
FILAMENTOUS HEMAGGLUTININ OF B. PERTUSSIS |
| 摘要 |
Nucleic acid and protein compositions are provided from B. pertussis which may find use in diagnosis, prevention and therapy of whooping cough. Particularly, an open reading frame encoding filamentous hemagglutinin precursors provided, with the intact protein for the filamentous hemagglutinin portion thereof, can be expressed in a wide variety of hosts, for use in the production of antibodies, for immunodiagnosis or therapy, or as vaccines for prophylactic purposes.
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| 申请公布号 |
CA1341123(C) |
申请公布日期 |
2000.10.17 |
| 申请号 |
CA19890614474 |
申请日期 |
1989.09.29 |
| 申请人 |
SCLAVO S.P.A.;THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
FALKOW, STANLEY;RELMAN, DAVID A.;RAPPUOLI, RINO;DOMENIGHINI, MARIO |
| 分类号 |
C12N15/09;A61K31/70;A61K38/00;A61K39/00;A61K39/10;A61K39/395;A61P37/04;C07K14/235;C12N1/21;C12N5/10;C12N9/12;C12P21/02;C12R1/01;C12R1/19;(IPC1-7):C12N15/31;A61P31/00;C12N1/20 |
主分类号 |
C12N15/09 |
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