发明名称 |
3-Pyridyloxymethyl heterocyclic ether compounds useful in controlling chemical synaptic transmission |
摘要 |
Novel 3-pyridyloxymethyl heterocyclic ether compounds of the formula: or the pharmaceutically-acceptable salts or prodrugs thereof are selective and potent ligands at neuronal nicotinic cholinergic channel receptors, and are effective in controlling synaptic transmission. Key intermediates and processes using this key intermediates to produce compounds of formula I with the variables defined in the specification are also described.
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申请公布号 |
US6127386(A) |
申请公布日期 |
2000.10.03 |
申请号 |
US19970844540 |
申请日期 |
1997.04.18 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
LIN, NAN-HORNG;HE, YUN;HOLLADAY, MARK W.;RYTHER, KEITH B.;LI, YIHONG;BAI, HAO |
分类号 |
C07D401/12;C07D401/14;C07D405/14;C07D409/14;(IPC1-7):A61K31/44;C07D471/02;C07D213/30 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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