发明名称 Thioalkyl alpha substituted pyrimidine compounds
摘要 The subject invention relates to pyrimidine-thioalkyl and alkylether compounds of Formula I and pyrimidine-thioalkyl and alkylethers of Formula I, where R4 is selected from the group consisting of -H or -NR15R16 where R15 is -H and R16 is -H, C1-C6 alkyl, -NH2 or R15 and R16 taken together with the -N form 1-pyrrolidino, 1-morpholino or 1-piperidino; and R6 is -S-C1-6 alkyl (preferably -SCH3); The compounds of Formula I are useful in the treatment of individuals who are HIV positive.
申请公布号 US6124306(A) 申请公布日期 2000.09.26
申请号 US19980157975 申请日期 1998.09.21
申请人 PHARMACIA & UPJOHN COMPANY 发明人 MORRIS, JOEL;ADAMS, WADE J.;FRIIS, JANICE M.;WISHKA, DONN G.
分类号 C07D239/58;A61K31/505;A61K31/506;A61K31/5377;A61P31/18;C07D239/26;C07D239/56;C07D401/12;C07D403/12;C07D405/12;C07D409/12;C07D413/12;C07D491/04;C07D491/048;(IPC1-7):C07D239/34 主分类号 C07D239/58
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