NUCLEOTIDE COMPOUNDS HAVING A CLEAVABLE LINKER

摘要

It has turned out to be valuable to use a disulfide-bonded cleavable nucleotide complex ac- cording formula I Dye - SS - Linker - Nucleotide (formula I) wherein Dye is a fluorophore; SS is a disulfide bridge; Linker is a useful linking group, such as - C .ident. - CH2 - NH - CO - CH2 -; and Nucleotide is a nucleotide chosen from the group of dCTP, dATP, dGTP, dTTP, ri- bonucleotides ar further modified nucleotides; in nucleic acid assay methods.