Mobilization of peripheral blood precursor cells by beta (1,3)-glucan

摘要

Methods for inducing mobilization of peripheral blood precursor cells, for elevating levels of peripheral blood precursor cells and facilitating hematopoietic reconstitution in a mammal are disclosed, comprising administering to the mammal an effective amount of an underivatized, aqueous soluble beta (1,3)-glucan in a triple helix conformation, which does not stimulate or prime the production of proinflammatory cytokines in vitro.