| 发明名称 |
SUBSTITUTED 3-METHYLENE-2-OXINDOLE-1-CARBOXAMIDES, THEIR USE AND PHARMACEUTICAL COMPOSITIONS BASED THEREON |
| 摘要 |
<p>Disclosed are compounds of the general formula (I) wherein R10, R11, R12 and R13 are hydrogen, alkyl or halogen and R is methyleneoxyalkanoyl, methyleneoxyalkenoyl or alkenoyl. These compounds are prodrugs of 3-acyl-2-oxindole-1-carboxamides, a class of known nonsteroidal antiinflammatory agents. Pharmaceutical preparations based on these prodrugs.</p> |
| 申请公布号 |
SK280929(B6) |
申请公布日期 |
2000.09.12 |
| 申请号 |
SK19950000912 |
申请日期 |
1993.10.20 |
| 申请人 |
PFIZER INC. |
发明人 |
BARTH WAYNE E.;COOPER KELVIN;KLEINMAN EDWARD F.;REITER LAWRENCE A.;ROBINSON RALPH P. |
| 分类号 |
A61K31/40;A61K31/404;A61K31/4433;A61K31/445;A61K31/465;A61K31/535;A61K31/55;A61P25/04;A61P29/00;A61P43/00;C07D209/04;C07D409/06;C07D409/14;C07F7/18;(IPC1-7):C07D409/06 |
主分类号 |
A61K31/40 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
