发明名称 COMPOSITIONS AND METHODS FOR USE IN TARGETING VASCULAR DESTRUCTION
摘要 <p>Treatment of warm-blooded animals having a tumor or non-malignant hypervascularization, by administering a sufficient amount of a cytotoxic agent formulated into a phosphate prodrug form having substrate specificity for microvessel phosphatases, so that microvessels are destroyed preferentially over other normal tissues, because the less cytotoxic prodrug form is converted to the highly cytotoxic dephosphorylated form.</p>
申请公布号 WO2000048606(A1) 申请公布日期 2000.08.24
申请号 US2000003996 申请日期 2000.02.16
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