Bivalent molecules that form an activating complex with an erythropoietin receptor
摘要
Antibodies and Bivalent molecules which activate erythropoietins and induce the proliferation or differentiation of erythroid progenitor cells are provided. Also provided are methods of using such bivalent molecules for drug discovery, diagnosis and treatment of disorders related to the activation of an erythropoietin receptor.
申请公布号
US6103879(A)
申请公布日期
2000.08.15
申请号
US19970876813
申请日期
1997.06.17
申请人
AXYS PHARMACEUTICALS, INC.
发明人
CHAOVAPONG, WARAK LEE;GIEBEL, LUTZ B.;KARKARIA, CYRUS;ROSS, MICHAEL J.;SCHNEIDER, HELMUT H.;SHOEMAKER, KEVIN