发明名称 THERAPY AND CONTROL OF DEVELOPMENT OF EYE
摘要 PROBLEM TO BE SOLVED: To obtain a medicine inducing the axial growth of the eyes of mature animals and useful for the therapy of the eyes for controlling the development of the eyes, especially for controlling the development of myopia, by adding a choline-operating agonist. SOLUTION: A medicine for inducing the axial growth of the eyes of mature animals contains a therapeutically effective amount of a choline-operating agonist. The choline-operating agonist is preferably carbamylcholine chloride, pilocarpine or M1 muscarine agonist McNeil-A-343. Pirenzepine, a muscarine antagonist having anti-choline eperability, is effective for blocking an axially growing myopia caused by the image blockage of the eyes of a chick. Telenzepine has an effect for blocking the axially growing myopia of mature animals. Other muscarine antagonists capable of being used as factors for blocking the axially growing myopia includes o-methoxy-sila-hexocyclium.
申请公布号 JP2000204049(A) 申请公布日期 2000.07.25
申请号 JP20000039526 申请日期 2000.02.17
申请人 TRUSTEES OF THE UNIV OF PENNSYLVANIA;UNIV PENNSYLVANIA 发明人 LATIES ALAN M;STONE RICHARD A
分类号 C07D405/06;A61K31/00;A61K31/14;A61K31/16;A61K31/27;A61K31/415;A61K31/4178;A61K31/46;A61K31/495;A61K31/55;A61K31/695;A61K45/00;A61P27/02;A61P27/10;A61P43/00;(IPC1-7):A61K45/00;A61K31/417 主分类号 C07D405/06
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