发明名称 |
METHODS OF EVALUATING TRANSPLANT REJECTION |
摘要 |
<p>The invention relates to methods of evaluating transplant rejection in a host comprising determining a heightened magnitude of gene expression of two out of three immune activation marker genes perforin, granzyme B and Fas ligand, in a tissue biopsy or peripheral blood mononuclear cell sample, particularly using reverse transcription polymerase chain reaction; methods of assessing antirejection therapy; and kits for use in evaluating transplant rejection.</p> |
申请公布号 |
EP1015639(A1) |
申请公布日期 |
2000.07.05 |
申请号 |
EP19980948342 |
申请日期 |
1998.09.22 |
申请人 |
BETH ISRAEL DEACONESS MEDICAL CENTER;CORNELL RESEARCH FOUNDATION, INC. |
发明人 |
STROM, TERRY, B.;VASCONCELLOS, LAURO;SUTHANTHIRAN, MANIKKAM |
分类号 |
G01N33/50;C12N15/09;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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