NOVEL MODULATORS OF PROSTAGLANDIN I2 (IP), RECEPTOR, METHOD OF OBTAINING THEM, PHARMACEUTIC AGENT AND METHOD OF OBTAINING SUCH AGENT

摘要

This invention relates to compounds which are generally IP receptor modulators, particularly IP receptor agonists, and which are represented by Formula I: wherein R<1>, R<2>, R<3>, R<4>, R<5>, A, and B are as defined in the specification, and individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds and methods for their use as therapeutic agents.