| 摘要 |
A method of improving cholesterol levels or diabetes status in subjects with hypercholesteremia or diabetes or at risk of developing such disorders includes identifying subjects having an allele and/or a genotype at a gene locus which positively correlates with greater success in improving cholesterol levels or diabetes status in hypercholesteremic or diabetic individuals, respectively, as compared with other alleles and/or genotypes at the same gene locus, and engaging the subject in exercise training for a period of time sufficient to improve the subject's cholesterol levels or diabetes status. Genotypic distinctions may be found, for example, in the glucose transport 4 gene, the myostatin exon 2 gene and the insulin receptor substrate-1 (IRS-1) gene. |
