发明名称 |
Modified coagulation agent |
摘要 |
The present invention is directed to a modified coagulation factor Xa which has an improved capacity of forming crystals compared to its native form. Such crystals or crystalline composition are especially useful for studies in crystalline form of the active catalytic site of factor Xa when it is complexed to a specific affinity ligand with inhibiting characteristics.
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申请公布号 |
US6069234(A) |
申请公布日期 |
2000.05.30 |
申请号 |
US19970994328 |
申请日期 |
1997.12.19 |
申请人 |
PHARMACIA & UPJOHN AB |
发明人 |
CHMIELEWSKA, JOANNA;LUNDQVIST, TOMAS;MASIALOU, ERIFILI;OGG, DEREK |
分类号 |
A61K38/00;A61P7/04;C12N9/64;(IPC1-7):A61K37/547;A61K37/02;C12N15/01;C07K13/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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