发明名称 |
DETERMINING SIGNAL TRANSDUCTION PATHWAYS |
摘要 |
Experimental and analytical methods enable reconstruction of signal transduction networks from gene expression profiles. Signal transduction pathways can be reverse-engineered by 1) experimentally manipulating individual genes, 2) generating cellular expression profiles, and 3) analyzing for common patterns among these profiles. Analysis of patterns among profiles permits reconstruction of pathways and networks of interrelationships among genes and their products.
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申请公布号 |
WO0026413(A1) |
申请公布日期 |
2000.05.11 |
申请号 |
WO1999US25703 |
申请日期 |
1999.11.03 |
申请人 |
AFFYMETRIX, INC.;OLINER, JONATHAN, D.;HUBBEL, EARL |
发明人 |
OLINER, JONATHAN, D.;HUBBEL, EARL |
分类号 |
G01N37/00;C12N15/09;C12N15/10;C12Q1/68;(IPC1-7):C12Q1/68;C12N15/00;C12N15/11;C12N15/85;C12P19/34;C07H21/04 |
主分类号 |
G01N37/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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