The present invention provides a method for producing a secretable polypeptide in a host cell, comprising overexpressing a peptidyl prolyl cis-trans isomerase in the host cell, thereby increasing the yield of the secreted polypeptide, and a novel peptidyl prolyl cis-trans isomerase from A. niger useful in such a method.
申请公布号
WO0018934(A1)
申请公布日期
2000.04.06
申请号
WO1999IB01669
申请日期
1999.09.30
申请人
DANISCO A/S;DERKX, PATRICK, M., F.;MADRID, SUSAN, M.