FLUORESCENCE POLARIZATION-BASED DIAGNOSTIC ASSAY FOR LEPTOSPIRA SEROVARS

摘要

In a homogeneous immunoassay for leptospirosis, antibodies specific for antigens present on the FlaB protein of Leptospira serovars bind to a diagnostic reagent comprising a recombinant FlaB protein labeled with fluorescein isothiocyanate, to give a detectable increase in fluorescence polarization. The assay is fast, simple to perform, and safe.