发明名称 |
Method of preparing a biological material for use in ophthalmology |
摘要 |
A collagen containing substrate comprising cattle basal membrane is conditioned by incubating the membranes in a mixture of pepsin, hyaluronidase and acetic acid and separating the collagen from the mixture. The mixture can include pepsin, hyaluronidase and a 0.5M solution of acetic acid in 1:1:10 proportions. The incubation is conducted for about 10 hours at about 45 DEG C. After incubation, collagen is separated from the mixture by centrifuging at a speed of 5000 to 30000 rpms for about 30 minutes. The collagen is mixed with polymerizable monomer and polymerized to form a gel that can be ground to form an intraocular or contact lens.
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申请公布号 |
US6037144(A) |
申请公布日期 |
2000.03.14 |
申请号 |
US19980192527 |
申请日期 |
1998.11.17 |
申请人 |
STAAR SURGICAL AG |
发明人 |
FEDOROV, SVYATOSLAV NIKOLAYEVICH;BAGROV, SERGEI NIKOLAYEVICH;LARIONOV, YEVGENY VIKTOROVICH;MALYSHEV, VLADIMIR BORISOVICH |
分类号 |
A61L27/24;C07K14/78;G02B1/04;(IPC1-7):C12P21/06;B29D11/00 |
主分类号 |
A61L27/24 |
代理机构 |
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