| 发明名称 |
3-amino-2-oxo-1-piperidnercetic derivatives as enzyme inhibitors |
| 摘要 |
The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.
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| 申请公布号 |
US6034215(A) |
申请公布日期 |
2000.03.07 |
| 申请号 |
US19970950270 |
申请日期 |
1997.10.14 |
| 申请人 |
CORVAS INTERNATIONAL, INC. |
发明人 |
SEMPLE, JOSEPH EDWARD;ARDECKY, ROBERT JOHN;NUTT, RUTH FOELSCHE;RIPKA, WILLIAM CHARLES;ROWLEY, DAVID C.;LIM-WILBY, MARGUERITA S. L.;BRUNCK, TERENCE KEVIN |
| 分类号 |
A61K38/55;A61K38/00;A61K38/05;A61P7/02;C07K;C07K5/06;C07K5/078;C07K5/083;C07K5/087;C07K5/09;C07K5/093;C07K5/097;(IPC1-7):A61K38/06 |
主分类号 |
A61K38/55 |
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