| 发明名称 |
Oligonucleotides having site specific chiral phosphorothioate internucleoside linkages |
| 摘要 |
Novel compounds that mimic and/or modulate the activity of wild-type nucleic acids. In general, the compounds are phosphorothioate oligonucleotides wherein the 5'-terminal internucleoside linkage or the 5'- and 3'-terminal linkages are modified. |
| 申请公布号 |
AU5102299(A) |
申请公布日期 |
2000.02.07 |
| 申请号 |
AU19990051022 |
申请日期 |
1999.07.14 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
PHILLIP DAN COOK;MUTHIAH MANOHARAN |
| 分类号 |
C12Q1/68;A61K31/7042;A61K31/7052;A61K31/7064;A61K31/7076;A61K31/7125;A61K48/00;C07H19/04;C07H19/10;C07H19/20;C07H21/00;C07H21/02;C07H21/04 |
主分类号 |
C12Q1/68 |
| 代理机构 |
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代理人 |
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