发明名称 |
PROTEASE SUSCEPTIBILITY II |
摘要 |
The present invention relates to: manipulation of the amino acid sequence of tropoelastin, particularly human tropoelastin, to modify its protease susceptibility; to tropoelastin derivatives having modified protease susceptibility; to peptidomimetic molecules which contain amino acid sequences which correspond to or incorporate the protease susceptible sequences of tropoelastin; and to uses of the tropoelastin derivatives and peptidomimetic molecules. The invention also relates to nucleic acid molecules and genetic constructs encoding the amino acid sequences of the derivatives and peptidomimetic molecules of the invention.
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申请公布号 |
WO0004043(A1) |
申请公布日期 |
2000.01.27 |
申请号 |
WO1999AU00580 |
申请日期 |
1999.07.19 |
申请人 |
THE UNIVERSITY OF SYDNEY;WEISS, ANTHONY, STEVEN |
发明人 |
WEISS, ANTHONY, STEVEN |
分类号 |
C12N15/09;A61K38/00;A61K38/17;A61L27/00;C07H21/04;C07K7/02;C07K7/04;C07K14/78;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12P21/02;(IPC1-7):C07K7/04;A61K38/39 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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