发明名称 |
1,3-dihydro-1-(phenylalkyl)-2H-imidazol-2-one compounds and their use for treating allergic, atopic or inflammatory diseases |
摘要 |
PCT No. PCT/EP96/01394 Sec. 371 Date Sep. 29, 1997 Sec. 102(e) Date Sep. 29, 1997 PCT Filed Mar. 28, 1996 PCT Pub. No. WO96/31485 PCT Pub. Date Oct. 10, 1996The present invention describes 1,3-dihydro-1-(phenylalkyl)-2H-imidazol-2-one compounds and their use for treating warm-blooded animals suffering from disease states related to an abnormal enzymatic or catalytic activity of phosphodiesterase IV (PDE IV), and/or disease states related to a physiologically detrimental excess of cytokines, in particular allergic, atopic and inflammatory diseases.
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申请公布号 |
US5994376(A) |
申请公布日期 |
1999.11.30 |
申请号 |
US19970930296 |
申请日期 |
1997.09.29 |
申请人 |
JANSSEN PHARMACEUTICA, N.V. |
发明人 |
FREYNE, EDDY JEAN EDGARD;DIELS, GASTON STANISLAS MARCELLA;ANDRES-GIL, JOSEIGNACIO;FERNANDEZ-GADEA, FRANCISCO JAVIER |
分类号 |
C07D233/32;A61K31/415;A61K31/4166;A61K31/44;A61K31/4427;A61K31/443;A61P11/00;A61P17/00;A61P29/00;A61P37/08;C07D233/36;C07D233/38;C07D233/70;C07D401/06;C07D401/12;C07D405/06;C07D405/12;(IPC1-7):A61K31/415 |
主分类号 |
C07D233/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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