PREPARATION OF ORGANIC ACIDS

摘要

This invention relates to a process for producing one or more org anic acids in high purity which process comprises (i) oxidizing in a liquid oxidation reactor one or more organic liquids with essentially pure oxygen or oxygen- enriched air containing at least about 50 % oxygen, at a temperature sufficiently stable to prevent cycling of reaction rate, to produce a crude reaction product fluid, and (ii) refining said crude reaction product fluid to give said one or more organic acids in high purity. The oxidation temperatur e is preferably controlled to within about ~3 ~C of a target temperature. The organic acids described herein are useful in a variety of applications, such as intermediates in the manufacture of chemical compounds, pharmaceutical manufacture and the like.