Method for the treatment of neurodegenerative diseases by administering VIP, an analogue, fragment or a conjugate thereof

摘要

A method for the treatment of neurodegenerative diseases comprising administering to a patient in need of such treatment a therapeutically effective amount of a peptide compound selected from the group consisting of: (i) vasoactive intestinal peptide (VIP); (ii) analogues of vasoactive intestinal peptide (VIP) in which one or more amino acids has been replaced, added or deleted without substantially altering the biological properties of the parent peptide; (iii) a conjugate being a peptide compound according to either of (i) and (ii) coupled to a lipophilic moiety; (iv) a physiologically active fragment of (i), (ii) and (iii); and (v) a functional derivative of any of (i), (ii), (iii) and (iv); optionally in combination with a pharmaceutically acceptable carrier.